Atypical Cogan's Syndrome

Cystoid macular oedema in Cogans syndrome-a case report

INTRODUCTION Cogan's Syndrome is typically characterised by a non syphilitic interstitial keratitis (IK), with or without conjunctivitis, iritis or subconjunctival bleeding and progressive sensorineural hearing loss within two years of ocular signs. Atypical ocular manifestations include episcleritis, scleritis, posterior scleritis, retinal artery occlusion, choroiditis, retinal vasculitis, and...

Atypical Symptoms of Acute Coronary Syndrome and Their Predictors

Atypical Hemolytic Uremic Syndrome

Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease characterized by complement overactivation. Inherited defects in complement genes and acquired autoantibodies against complement regulatory proteins have been described. Incomplete penetrance of mutations in all predisposing genes is r...

Atypical Meigs' syndrome.

Large blood-stained pleural effusions, especially in young patients, are unusual and may be caused by metastatic disease in the chest, a large pulmonary infarction, and, rarely, pulmonary tuberculosis. Meigs' syndrome is an uncommon cause of pleural effusion associated with ascites and a benign ovarian tumour, most often a fibroma. The fluid is usually clear but occasionally blood-stained. The ...

Atypical haemolytic uraemic syndrome.

The haemolytic uraemic syndrome (HUS) is characterized by the triad of thrombocytopenia, microangiopathic haemolytic anaemia and acute renal failure. HUS may be classified as either diarrhoeal-associated or non-diarrhoeal/atypical (aHUS). aHUS has recently been shown to be a disease of complement dysregulation, with 50% of cases involving the complement regulatory genes, factor H (CFH), membran...